Current funding opportunities

Please note, the application for all KPMP Opportunity Pool FOAs (except for KPMP Travel Grants) is the standard PHS 398 form.

RFA-KPMP-OP-20-004: New Cohorts

Perform KPMP research biopsies on existing kidney disease cohorts

There is a critical need to obtain high-quality biopsies from diverse individuals with kidney disease linked to extensive biosamples and longitudinal clinical phenotypic data to fully realize the goals of the KPMP. This solicitation aims to form new collaborative partnerships with existing kidney disease cohorts who are currently not performing biopsies by providing KPMP opportunity pool funds to add research biopsies.

Strong applications will propose to ethically and safely obtain, share, and harmonize at least 20 human kidney research biopsies per year with the necessary diversity (sex, age, race, and ethnicity) and metadata (including extensive longitudinal clinical data) to meet the objectives of the KPMP.  Applicants must employ current KPMP participant informed consent process and operational protocols developed for biopsy performance, tissue processing, data and biosample capture, etc. (https://kpmp.org/researcher-resources/). Existing kidney disease cohorts that already include a biopsy are not eligible for this funding opportunity, but are encouraged to submit a KPMP glue grant application (full details at https://kpmp.org/wp-content/uploads/2019/03/KPMP-OP-RFA_Glue_Grants_2019-03-26.pdf).

Applicants must utilize the KPMP single IRB, Washington University St. Louis. Applicants are encouraged to provide a written commitment from their local IRB demonstrating willingness to rely on the single IRB, and to obtain consent for people to participate in the KPMP and for the collection, use, and sharing of human samples and appropriate affiliated metadata for research purposes. Award is contingent on single IRB approval.

Five (5) page applications may request up to $300,000 total costs per year for two years .

ID NUMBER: RFA-KPMP-OP-20-004
EARLIEST SUBMISSION DATE: 
March 1, 2020
SUBMISSION DEADLINE: April 20, 2020 by 5 p.m. Eastern

RFA-KPMP-OP-20-003: Enhanced Phenotyping

Test tools or methods to enhance KPMP clinical phenotyping

Given the breadth and depth of molecular data being generated by interrogating KPMP biopsies, there is a critical need to develop and implement new tools or methods to achieve greater breadth and depth of longitudinal clinical phenotypic data describing our KPMP patient participants (https://kpmp.org/researcher-resources/). Areas of need include, but are not limited to, physiology and imaging.

This solicitation aims to form new collaborative partnerships by providing KPMP opportunity pool funds to applicants proposing to enhance the longitudinal clinical phenotyping of KPMP patient participants at a single existing KPMP Recruitment Site (RS). All data and protocols from this first “test” phase must be completed and uploaded to the KPMP CH within the first year. Newly identified tools or methods that add significant value to the KPMP will be eligible for a second year of KPMP funding and perhaps incorporation across multiple KPMP RSs.

Five (5) page applications may request up to $100,000 total costs in year one and $200,000 total costs in year two (for a total of 2 years)

ID NUMBER: RFA-KPMP-OP-20-003
EARLIEST SUBMISSION DATE: 
March 1, 2020
SUBMISSION DEADLINE: April 20, 2020 by 5 p.m. Eastern

RFA-KPMP-OP-20-002: New TIS Tech

Develop and test novel tissue interrogation technologies

There is a critical need to develop new tools and technologies to interrogate human kidney tissue with the necessary molecular breadth and spatial resolution to fully realize the goals of the KPMP. This solicitation aims to form new collaborative partnerships by providing KPMP opportunity pool funds to applicants proposing to deploy novel tissue interrogation technologies on human kidney tissue provided centrally by the KPMP (e.g. nephrectomy).

Proposed technologies must not overlap with currently funded KPMP approaches (for full details see https://kpmp.org/consortium-members/). All data from this first “test” phase – which must be completed and uploaded, along with protocols, to the KPMP CH within the first year – will be rigorously compared to existing KPMP technologies and other tissue interrogation platforms funded by this FOA.

Awardees with newly identified technologies that add significant value to the KPMP will be eligible for a second year of KPMP funding and perhaps approval to interrogate KPMP research biopsies obtained from KPMP patient participants. The KPMP Tissue Interrogation Site Approval Committee (TISAC) will evaluate all technologies prior to their utilization on KPMP biopsies.

Five (5) page applications may request up to $100,000 total costs per year for two years.

ID NUMBER: RFA-KPMP-OP-20-002
EARLIEST SUBMISSION DATE: 
March 1, 2020
SUBMISSION DEADLINE: April 20, 2020 by 5 p.m. Eastern

RFA Glue Grant

Apply for a Glue Grant to partner with the KPMP

This solicitation aims to form new collaborative partnerships by providing “glue grants” to investigators working in areas of high relevance to the KPMP and currently supported by other significant non-KPMP funding sources. Examples of other significant funding sources include, but are not limited to, an NIH R01, RC2, DP3, or U01 award, or a VA MERIT award.

Successful glue grants are expected to be mutually beneficial. Applicants should describe how their “parent” project will benefit from being part of the KPMP and how the KPMP will benefit from partnering with the “parent” project. Specifically, glue grant funding will provide a supplement of up to $60,000 total costs per year to the “parent” project to support sharing, harmonization, and integration with the KPMP of relevant data, samples, tissues, reagents, technologies, tools, software, analytic pipelines, expertise, etc.

Five (5) page applications may request up to $5,000 total costs per month and are invited on a rolling basis.

SUBMISSION DEADLINE: April 20, 2020 by 5 p.m. Eastern

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