Opportunity Pool Funding
Recent advances in multi-scale interrogation of human tissue and single cells have set the stage for precision medicine to be applied to kidney disease. The objectives of the Kidney Precision Medicine Project are to ethically and safely obtain and evaluate human kidney biopsies from participants with Acute Kidney Injury (AKI) or Chronic Kidney Disease (CKD), create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways and targets for novel therapies. Learn more about the KPMP protocols and processes.
The Opportunity Pool process
The Opportunity Pool is managed by the Central Hub and administered by Mount Sinai. Ian de Boer, MD (University of Washington) and Laura Mariani, MD (University of Michigan) serve as Opportunity Pool Co-Directors. The Opportunity Pool is responsible for the following:
- Facilitating communication with applicants
- Recruitment of external peer reviewers
- Correspondence with reviewers
- Collection of the critiques
- Disbursement and accounting of funds
The Central Hub closely supervises the external peer review process and serves as a resource for potential applicants.
KPMP Travel Grants
The Kidney Precision Medicine Project supports professional development opportunities for early-career investigators. One such opportunity allows investigators to attend KPMP Steering Committee meetings and present posters on their research as relevant to KPMP.
Early-stage investigators who attended past meetings have learned about KPMP protocols in development, scientific technologies to be applied to the interrogation of kidney biopsy tissue, the role of patient and community engagement in KPMP, and how data management and visualization tools will be applied to the creation of the Kidney Tissue Atlas.
In addition to the opportunity to present during the meeting’s poster session, early-stage investigators are awarded a travel stipend. Interested candidates must submit an NIH biosketch and an abstract of their research. Abstracts will undergo a peer-review process for scoring.
Current Opportunities
Early Career Investigator Travel Grants for March 2025 KPMP Meeting
ID Number:
Earliest submission date:
Application due date:
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Past Funding opportunities & Awardees
Awardees:
Ensemble framework for predicting regulatory variants in rare kidney cell types.
Dongwon Lee Boston Children's Hospital
Visual Analytics for Exploration and Hypothesis Generation Using Highly Multiplexed Spatial Data of Tissues and Tumors
Sandro Santagata Harvard Medical School
3D Image-Omics Integration for Spatial Transcriptomics in High Definition
Yuankai Huo Vanderbilt University
Diabetes StudY in Nephropathy And other Microvascular cOmplications (DYNAMO)
Thomas Coffman Duke-NUS Medical School
Awardees:
Columbia University
Awardees:
No awards were issued.
Awardees:
Hamid Rabb (Johns Hopkins)
Sequencing KPMP AKI stool microbiome samples
Kalani Raphael (OHSU) & John Asplin (Litholink)
Enhancing the phenotype of KPMP participants with measurements of urinary electrolytes and acid-base parameters
Metabolon Inc
Metabolite profiling of KPMP participants
Somalogic
Somascan 7,000 proteomics analysis of EDTA plasma and urine samples from the KPMP cohort
Wassim Obeid & Chirag Parikh (Johns Hopkins)
Measurement of blood and urinary biomarkers to enhance the KPMP tissue atlas
Awardees:
Awardees:
Miguel Vazquez & Bob Toto (UT Southwestern)
Kidney Precision Medicine Project, COVID-19 research at KPMP sites
Stewart Lecker & Sylvia Rosas (Beth Israel Deaconess Medical Center)
Acute Kidney Injury and COVID-19: KPMP substudy
Steve Menez & Chirag Parikh (Johns Hopkins University)
Kidney Injury in Patients with COVID-19: A Sub-study of the Kidney Precision Medicine Project
Perry Wilson & Dennis Moledina (Yale University)
Phenotyping AKI in COVID-19 Cohort (PACC) Study
Awardees:
Jonathan Taliercio, DO (Cleveland Clinic)
Cleveland CRIC KPMP
Awardees:
Lloyd Cantley, MD (Yale University)
Spatially preserved cell state phenotyping using Imaging Mass Cytometry-Kidney-MAPPS
Anna Greka, MD, PhD & Jamie Marshall, PhD (Broad Institute)
Slide-seq: spatial transcriptomic technology for tissue interrogation
Michael Rauchman, MDCM (Washington University St. Louis)
Chromatin Profiling of Nephrectomy and Kidney Biopsy Tissues
Awardees:
Ari Pollack, MD (Seattle Children’s/University of Washington)
Designing a Visual Decision Aid for Shared Decision Making after Renal Biopsy
Awardees:
Sus Waikar, MD, MPH (Boston University)
Anand Srivastava, MD, MPH (Northwestern University)
Pottumarthi Prasad, PhD (Northshore)
ADVANCING MULTIPARAMETRIC KIDNEY FUNCTIONAL MRI TO PHENOTYPE INDIVIDUALS WITH CKD
Sus Waikar, MD, MPH (Boston University)
Petter Bjornstad, PhD (University of Colorado)
Kidney Physiology Phenotyping in the Kidney Precision Medicine Project
Ian de Boer, MD (University of Washington)
Sylvia Rosas, MD (Joslin Diabetes Center)
Advanced retinal phenotyping to identify mechanistic pathways in chronic kidney disease
Awardees:
Jeffrey Spraggins, PhD & Richard Caprioli, PhD (Vanderbilt University)
Integrating the VU Biomolecular Multimodal Imaging Center of HuBMAP with the Kidney Precision Medicine Project
Katy Borner, PhD (Indiana University)
Harmonizing KPMP/HuBMAP Data: Developing Common Coordinate Framework UI
Anant Madabhushi, PhD (Case Western Reserve)
HistoTools: A suite of digital pathology tools for quality control, annotation, and dataset identification
Pinaki Sarder, PhD (University of Buffalo)
A Computational Renal Pathology Suite for KPMP
Awardees:
Minnie Sarwal, MD (UCSF)
Building Health Kidney Tissue Repository for KPMP
James Williams, PhD (Indiana University)
Healthy Reference Tissue for KPMP
E. Steven Woodle, MD (University of Cincinnati)
Kidney Precision Medicines Project Healthy Living Kidney Donor Tissue Repository
Kalani Raphael, MD (OHSU) & John Asplin, MD (Litholink)
Enhancing the phenotype of KPMP participants with measurements of urinary electrolytes and acid-base parameters
Metabolon Inc
Metabolite profiling of KPMP participants
Somalogic
Somascan 7,000 proteomics analysis of EDTA plasma and urine samples from the KPMP cohort
Wassim Obeid, PhD & Chirag Parikh, MD (Johns Hopkins)
Measurement of blood and urinary biomarkers to enhance the KPMP tissue atlas
Awardees:
Petter Bjornstad, MD (University of Colorado)
Tissue based integrative biology of early diabetic kidney disease in youth-onset type 2 diabetes
Awardees:
Steve Bogen, MD, PhD (Boston Cell Standards, LLC)
Analytic Calibrators and Controls Core Resource for Protein Biomarker Testing
Hongping Ye, PhD (UTHSA)
Human Kidney Mimetic Tissue Using Endogenous Lips and Metabolites as Secondary Standards
Travel grants
Awardees:
Ramya Narasimhan Boston University
Nanditha Anandakrishnan Icahn School of Medicine at Mount Sinai
Sok Cin Tye Joslin Diabetes Center
Amin Abedini University of Maryland Medical Center Midtown Campus
Thai Huy Pham Vanderbilt University
Jovan Tanevski Heidelberg University
Jonathan Nelson University of Southern California
Sayat Mimar University of Florida
Azuma Nanamatsu Indiana University
Katerina Trachtova Jain Lab, Washington University in St. Louis, MO
Leila Hejazi SygnaMap
Danielle Janosevic Indiana University
Awardees:
Fan Fan, Emory University, Atlanta
Chao Zhang, Boston University School of Medicine
Huu Hien Huynh, University of Washington
Insa Schmidt, Boston University
Pei Su, Northwestern University
Allison Esselman, Vanderbilt University
Jin Zhou, Duke University
Marina de Cos Gomez, Icahn School of Medicine at Mount Sinai
Ricardo Melo Ferreira, Indiana University
Abdulsalam Soofi, University of Michigan
Leah Guthrie, University of California, Berkeley
Yuankai Huo, Vanderbilt University
Xiao Sun, University of Illinois Chicago
Debora L. Gisch, Indiana University
Christoph Zechner, UT Southwestern
Awardees:
Awardees:
Seth Winfree (Indiana University)
Sean Eddy (University of Michigan)
Kasra Rezaei (University of Washington)
Abhijit Naik (University of Michigan)
Christine Limonte (University of Washington)
Hyun Jun Jung (Johns Hopkins University)
Insa Schmidt (Harvard University)
Angela Sabo (Indiana University)
Tianyi Zhou (Northeastern University)
Wenqing Yin (Boston University)
Ari Pollack (University of Washington)
Awardees:
Daria Barwinska*(4) (Indiana University)
Pavan Bhatraju*(1) (University of Washington)
Yijiang Chen (Case Western Reserve University)
Scott Kennedy (University of Washington)
Jessica Lukowski (Pacific Northwest National Laboratory)
Anna Mathew (University of Michigan)
Abhijit Naik (University of Michigan)
Annapurna Pamreddy (University of Texas Health Science Center, San Antonio)
Colin Reily (University of Alabama at Birmingham)
Pinaki Sarder (University at Buffalo)
Insa Schmidt (Boston University Medical Center, Renal Section)
Yanbao Yu (J. Craig Venter Institute)
Dong Zhou (University of Pittsburgh School of Medicine)
*(n) = previous awardee & number of times awarded
Awardees:
Barwinska, Daria (Indiana University)
Charu, Vivek (Stanford)
Gonzalez-Vicente, Agustin (Cleveland Clinic)
Hinson, Jeremiah (John’s Hopkins University)
Jayapandian, Cathe)rine (Center for Computational Imaging and Personalized Diagnostics (CCIPD))
Kolachalama, Vijaya (Boston University)
Spraggins, Jeffrey (Vanderbilt University)
Sreelatha, Anju (UT Southwestern)
Van de Plas, Raf (Vanderbilt University)
Velickovic, Dusan (Pacific Northwest National Laboratory)
Walsh, Michael (University of Illinois at Chicago)
Zhang, Guanshi (UT Health San Antonio)
Awardees:
Lindstrom, Nils (USC)
Avigan, Zach (Yale)
Zhang, Guanshi (UTHSA)
Barwinska, Daria (Indiana University)
Gonzalez-Vicente, Agustin (Cleveland Clinic)
Rashmi, Priyanka (UCSF)
Schoreder, Andrew (UCSF)
Srivastava, Anand (Northwestern University)
Schaub, Jen (University of Michigan)
Amodu, Afolarin (Brigham Women & Children)
Gregg, Lucile (UT Southwestern)
Zhang, Yu (Brigham Women & Children)
Cobb, Jason (Emory)
Sohaney, Ryann (University of Michigan)
Ugwuowo, Ugochukwu (Yale)
Awardees:
Zhang, Guanshi (UTHSA)
Akilesh, Shreeram (University of Washington)
Lee, Kim (Mount Sinai)
Moledina, Dennis (Yale)
Bhargava, Rhea (Beth Israel Deaconess Medical Center)
Wilson, Parker (Washington University St. Louis)
Meliambro, Kristin (Mount Sinai)
Barwinska, Daria (Indiana University)
Palsson, Ragnar (Brigham Women & Children)
Schroeder, Andrew (UCSF)
Ferre, Silvia (UT Southwestern)
Hayden, Robert (Harvard University)
Kliegel, Judith (Yale)
Mansour, Sherry (Yale)
Velickovic, Dusan (Pacific Northwest National Lab)
Awardees:
Palsson, Ragnar (Brigham/Harvard)
Bhargava, Rhea (BIDMC)
Almaani, Salem (Ohio State University Wexner Medical Center)
Nguyen, Jane Kim (Cleveland Clinic)
Awardees:
Hoover, Paul (Broad Institute/UMichigan)
Poyan-Mehr, Ali (Harvard)
Barwinska, Daria (Indiana University)
Winfree, Seth (Indiana University)
Lee, Kyung (Kim) (Mount Sinai)
Dieter, Brad (Providence Medical Research Center)
Zhang, Guanshi (University of Texas Health San Antonio)
Akilesh, Shreeram (University of Washington)
Bhatraju, Pavan (University of Washington)
Sweetwyne, Mariya (University of Washington)
Singh, Nikhil (Yale)
